POLYMERASE CHAIN-REACTION ANALYSIS OF TUMOR CONTAMINATION IN PERIPHERAL-BLOOD STEM-CELL HARVESTS

被引：12

作者：

LANGLANDS, K

ANDERSON, JS

PARKER, AC

ANTHONY, RS

机构：

[1] Department of Haematology, Royal Infirmary, Edinburgh

来源：

INTERNATIONAL JOURNAL OF CELL CLONING | 1992年 / 10卷

关键词：

POLYMERASE CHAIN REACTION; MINIMAL RESIDUAL DISEASE; PERIPHERAL BLOOD STEM CELLS;

D O I：

10.1002/stem.5530100732

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Polymerase chain reaction (PCR) analysis using T-cell receptor delta chain gene (TCR-delta), immunoglobulin heavy chain gene (IgH) and t(14; 18) translocation was used to assess minimal residual disease (MRD) in PBSC and bone marrow from patients with leukaemia and lymphoma. PCR positivity was found in a proportion of PBSC harvests collected following standard chemotherapy.

引用

页码：95 / 97

页数：3