Two-dimensional effects are considered as promising for getting the conditions required for effective thermonuclear burning in cylindrical magnetohydrodynamic targets without tritium, A set of numerical calculations has been performed for large-scale driver energy (E(0) approximate to 300 MJ) in the hydraulic (1.5D) approximation. It is also suggested that a driver energy E(0) approximate to 300 MJ may be sufficient for complex deuterium targets, provided that the effects of the two-dimensional magnetic hydrodynamics are fully exploited.