IS CHOLESTASIS DUE TO MICROFILAMENT FAILURE

被引：15

作者：

FRENCH, SW

机构：

[1] UNIV CALIF DAVIS, SCH MED, DAVIS, CA 95616 USA

[2] VET ADM HOSP, SERV LAB, MARTINEZ, CA USA

来源：

HUMAN PATHOLOGY | 1976年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0046-8177(76)80034-2

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

The theory that cholestasis is a result of the failure of pericanalicular microfilaments to contract is discussed. The theory rests on the supposition that microfilaments contain contractile proteins. Agents that affect microfilament function are shown to cause cholestasis. Experiments in man and rat draw analogies between smooth muscle contraction and microfilaments, and hormonal control of both systems is discussed. Biochemical and physiological evidence is cited throughout as proof.

引用

页码：243 / 244

页数：2