REVERSION OF A LONG-LIVING, UNDIFFERENTIATED MUTANT OF PODOSPORA-ANSERINA BY COPPER

被引：27

作者：

MARBACH, K ^{[1
]}

FERNANDEZLARREA, J ^{[1
]}

STAHL, U ^{[1
]}

机构：

[1] TECH UNIV BERLIN,FACHGEBIET MIKROBIOL & GENET,D-13355 BERLIN,GERMANY

来源：

CURRENT GENETICS | 1994年 / 26卷 / 02期

关键词：

PODOSPORA ANSERINA; COPPER METABOLISM; PLEIOTROPIC MUTATION; PHENOLOXIDASES;

D O I：

10.1007/BF00313809

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Podospora anserina nuclear mutant grisea displays an undifferentiated growth phenotype (diminished production of aerial hyphae), is female sterile (lack of perithecia), has a prolonged life-span compared to the wild-type strain, and lacks detectable phenoloxidase (laccase and tyrosinase) activity. Reversion of all of these characteristics to those of the wild-type phenotype was accomplished by supplementing the growth medium with extra amounts of copper salts. These results indicate that the primary defect of the grisea strain is in its copper uptake and/or distribution in the cells.

引用

页码：184 / 186

页数：3

共 25 条

[1] A SITE-SPECIFIC DELETION IN MITOCHONDRIAL-DNA OF PODOSPORA IS UNDER THE CONTROL OF NUCLEAR GENES [J].

BELCOUR, L ;

BEGEL, O ;

PICARD, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (09) :3579-3583

[2] COPPER TRANSFER BETWEEN NEUROSPORA COPPER METALLOTHIONEIN AND TYPE-3 COPPER APOPROTEINS [J].

BELTRAMINI, M ;

LERCH, K .

FEBS LETTERS, 1982, 142 (02) :219-222

[3] EXCRETION OF LACCASE BY SYCAMORE (ACER-PSEUDOPLATANUS L) CELLS .2. EFFECTS OF A COPPER DEFICIENCY [J].

BLIGNY, R ;

GAILLARD, J ;

DOUCE, R .

BIOCHEMICAL JOURNAL, 1986, 237 (02) :583-588

[4] ABSENCE OF LACCASE FROM YELLOW-SPORED MUTANTS OF ASPERGILLUS-NIDULANS [J].

CLUTTERBUCK, AJ .

JOURNAL OF GENERAL MICROBIOLOGY, 1972, 70 (MAY) :423-+

[5] DIE INCOMPATIBILITATSBEZIEHUNGEN ZWISCHEN GEOGRAPHISCHEN RASSEN VON PODOSPORA-ANSERINA (CES) REHM .1. DIE GENETISCHE ANALYSE DER SEMI-INCIMPATIBILITAT [J].

ESSER, K .

ZEITSCHRIFT FUR INDUKTIVE ABSTAMMUNGS UND VERERBUNGSLEHRE, 1956, 87 (04) :595-624

[6] GENES INHIBITING SENESCENCE IN ASCOMYCETE PODOSPORA-ANSERINA [J].

ESSER, K ;

KELLER, W .

MOLECULAR & GENERAL GENETICS, 1976, 144 (01) :107-110

[7] INTRACELLULAR COPPER TRANSPORT IN CULTURED HEPATOMA-CELLS [J].

FREEDMAN, JH ;

PEISACH, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 164 (01) :134-140

[8] COPPER ACCUMULATION IN THE CELL-WALL-DEFICIENT SLIME VARIANT OF NEUROSPORA-CRASSA - COMPARISON WITH A WILD-TYPE STRAIN [J].

GERMANN, UA ;

LERCH, K .

BIOCHEMICAL JOURNAL, 1987, 245 (02) :479-484

[9] REACTIVE OXYGEN SPECIES ASSOCIATED WITH CELL-DIFFERENTIATION IN NEUROSPORA-CRASSA [J].

HANSBERG, W ;

DEGROOT, H ;

SIES, H .

FREE RADICAL BIOLOGY AND MEDICINE, 1993, 14 (03) :287-293

[10] LACCASE LOCALIZED IN HULLE CELLS AND CLEISTOTHECIAL PRIMORDIA OF ASPERGILLUS-NIDULANS [J].

HERMANN, TE ;

KURTZ, MB ;

CHAMPE, SP .

JOURNAL OF BACTERIOLOGY, 1983, 154 (02) :955-964

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