A SEMIAUTOMATED METHOD FOR MEASURING BRAIN INFARCT VOLUME

被引：1607

作者：

SWANSON, RA

MORTON, MT

TSAOWU, G

SAVALOS, RA

DAVIDSON, C

SHARP, FR

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT PHYSIOL,SAN FRANCISCO,CA 94143

[2] UNIV CALIF SAN FRANCISCO,DEPT NEUROL,SAN FRANCISCO,CA 94143

来源：

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM | 1990年 / 10卷 / 02期

关键词：

Brain; Infarction; Nissl stain; Succinate dehydrogenase;

D O I：

10.1038/jcbfm.1990.47

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

An accurate, reproducible method for determining the infarct volumes of gray matter structures is presented for use with presently available image analysis systems. Areas of stained sections with optical densities above that of a threshold value are automatically recognized and measured. This eliminates the potential error and bias inherent in manually delineating infarcted re-gions. Moreover, the volume of surviving normal gray matter is determined rather than that of the infarct. This approach minimizes the error that is introduced by edema, which distorts and enlarges the infarcted tissue and surrounding white matter.

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收藏

页码：290 / 293

页数：4

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