THE SYNTHESIS OF PSEUDO-SUGARS RELATED TO ALLOSAMIZOLINE

被引:16
作者
CORBETT, DF [1 ]
DEAN, DK [1 ]
ROBINSON, SR [1 ]
机构
[1] SMITHKLINE BEECHAM PHARMACEUT,GREAT BURGH,YEW TREE BOTTOM RD,EPSOM KT18 5XQ,SURREY,ENGLAND
关键词
PSEUDO-SUGAR; ALLOSAMIDIN; ALLOSAMIZOLINE; CHITINASE INHIBITOR; FERRIER REARRANGEMENT;
D O I
10.1016/S0040-4039(00)60336-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The syntheses of two bicyclic pseudo-sugars related to allosamizoline, the aminocyclitol component of the chitinase inhibitor allosamidin, are described. These carbocyclic pseudo-sugars containing a cyclohexane ring were synthesised from D-glucosamine via a Ferrier rearrangement.
引用
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页码:1525 / 1528
页数:4
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