TOPOGRAPHIC DIFFERENCES OF H-1-NMR RELAXATION-TIMES (T(1), T(2)) IN THE NORMAL INTERVERTEBRAL DISC AND ITS RELATIONSHIP TO WATER-CONTENT

被引：43

作者：

CHATANI, K

KUSAKA, Y

MIFUNE, T

NISHIKAWA, H

机构：

[1] Department of Orthopaedic Surgery, Kyoto Prefectural University of Medicine, Kyoto

[2] Department of Physiology, Meiji College of Oriental Medicine, Kyoto

来源：

SPINE | 1993年 / 18卷 / 15期

关键词：

INTERVERTEBRAL DISC; H-1-NMR RELAXATION TIMES (T(1); T(2)); WATER CONTENT;

D O I：

10.1097/00007632-199311000-00022

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

H-1-nuclear magnetic resonance studies, in vitro, on normal intervertebral discs dissected from adult bovine (3-or 4-year-old) coccygeal vertebrae were performed to clarify topographic differences in relaxation times (T1, T2) and relationships between the relaxation times and water content. Immediately after death, intervertebral discs were dissected from 1st/2nd and 2nd/3rd coccygeal vertebrae and divided into three specimens: the nucleus pulposus, inner anulus fibrosus, and outer anulus fibrosus. T1, T2, and water content were measured for the specimens collected from 15 intervertebral discs (untreated group). Secondly, specimens were similarly collected from 12 intervertebral discs and were treated to changed water contents (dehydrated group and hydrated group). For each treated specimen, T1, T2, and water content were measured. The results showed highly significant differences (P < 0.01) in T1 values among the nucleus pulposus, inner anulus fibrosus, and outer anulus fibrosus, and also in T2 values between the nucleus pulposus and anulus fibrosus. In each of the nucleus pulposus and anulus fibrosus, a positive linear relationship (r = 0.97, P < 0.01) was found between T1 and water content. The respective regression lines for the nucleus pulposus and anulus fibrosus had different slopes, and the slope of the nucleus pulposus was significantly greater than that of the anulus fibrosus. Thus, the decrease in water content shortens the T1 in intervertebral discs, and changes in water content have a greater influence on T1 in the nucleus pulposus than in the anulus fibrosus. Concerning the relationship between T2 and water content, the shortening of T2, according to the decrease in water content, was found at approximately 75% or more of water content in each of the nucleus pulposus and anulus fibrosus. No marked changes in T2 were found below 75% of water content. In conclusion, T1 and T2 vary within the nucleus pulposus, inner anulus fibrosus, and outer anulus fibrosus, and have characteristic relationships with water content in normal intervertebral discs.

引用

页码：2271 / 2275

页数：5

共 23 条

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