NOVEL STRATEGIES FOR THE CONSTRUCTION OF COMPLEX POLYCYCLIC ETHER FRAMEWORKS - STEREOCONTROLLED SYNTHESIS OF THE FGHIJ RING-SYSTEM OF BREVETOXIN-A

被引：69

作者：

NICOLAOU, KC ^{[1
]}

VEALE, CA ^{[1
]}

HWANG, CK ^{[1
]}

HUTCHINSON, J ^{[1
]}

PRASAD, CVC ^{[1
]}

OGILVIE, WW ^{[1
]}

机构：

[1] UNIV CALIF SAN DIEGO, DEPT CHEM, LA JOLLA, CA 92093 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1991年 / 30卷 / 03期

关键词：

D O I：

10.1002/anie.199102991

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Almost one hindered steps were necessary to synthesize the FGHIJ ring framework 1 of brevetoxin A in its naturally occurring enantiomeric form from the readily accessible carbohydrates D‐mannose, 2‐deoxy‐D‐ribose, and tri‐O‐acetyl‐D‐glucal. Despite the large number of steps the synthesis is highly convergent, which makes the efficiency even more impressive. (Figure Presented.) Copyright © 1991 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：299 / 303

页数：5

共 11 条

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