HYPERSENSITIVITY SYSTEMIC REACTION FOLLOWING INTRAVESICAL BACILLUS-CALMETTE-GUERIN - SUCCESSFUL TREATMENT WITH STEROIDS

被引：59

作者：

MOLINA, JM

RABIAN, C

DAGAY, MF

MODAI, J

机构：

[1] HOP ST LOUIS,DEPT IMMUNOL,F-75010 PARIS,FRANCE

[2] HOP ST LOUIS,DEPT PATHOL,F-75010 PARIS,FRANCE

来源：

JOURNAL OF UROLOGY | 1992年 / 147卷 / 03期

关键词：

BCG VACCINE; BLADDER NEOPLASMS; HEPATITIS; PULMONARY FIBROSIS;

D O I：

10.1016/S0022-5347(17)37354-8

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Intravesical bacillus Calmette-Guerin (BCG) is an effective treatment for superficial bladder carcinoma. Serious complications, including disseminated BCG infection, are infrequent. We report a case of granulomatous hepatitis with pneumonitis following intravesical administration of BCG. Cultures for mycobacteria were negative in sputum, bronchoalveolar lavage, liver and blood specimens. All symptoms disappeared within days after steroid therapy. Hypersensitivity reaction should be considered in patients with systemic symptoms after immunotherapy with BCG.

引用

页码：695 / 697

页数：3

共 19 条

[1] ANTIBIOTIC AND STEROID-THERAPY OF MASSIVE SYSTEMIC BACILLUS CALMETTE-GUERIN TOXICITY [J].