ABSENCE OF BETA-GALACTOSIDASE (LACTASE) ACTIVITY FROM INTESTINAL BRUSH-BORDERS OF SUCKLING MACROPODS - IMPLICATIONS FOR MECHANISM OF LACTOSE ABSORPTION

被引：11

作者：

CRISP, EA ^{[1
]}

CZOLIJ, R ^{[1
]}

MESSER, M ^{[1
]}

机构：

[1] UNIV SYDNEY, DEPT BIOCHEM, SYDNEY, NSW 2006, AUSTRALIA

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY | 1987年 / 88卷 / 03期

关键词：

D O I：

10.1016/0305-0491(87)90265-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Neutral .beta.-galactosidase (lactase) activity was absent from crude brush borders of small intestines of three species of suckling macropods (kangaroos and wallabies), even though the intestinal mucosal homogenates had high .beta.-galactosidase activities. 2. These activities were entirely due to an intracellular acid .beta.-galactosidase, probably located in lysosomes. 3. The results suggest that the absorptive-digestive mechanism for lactose in macropods is fundamentally different from that in eutherian mammals.

引用

页码：923 / 927

页数：5

共 29 条

[1] THE INGESTION OF PROTEINS AND COLLOIDAL MATERIALS BY COLUMNAR ABSORPTIVE CELLS OF THE SMALL INTESTINE IN SUCKLING RATS AND MICE [J].

CLARK, SL .

JOURNAL OF BIOPHYSICAL AND BIOCHEMICAL CYTOLOGY, 1959, 5 (01) :41-+

[2]

COLLINS JG, 1981, CARBOHYD RES, V92, P136, DOI 10.1016/S0008-6215(00)85988-1

[3] ASSAY OF INTESTINAL DISACCHARIDASES [J].

DAHLQVIST, A .

ANALYTICAL BIOCHEMISTRY, 1968, 22 (01) :99-+

[4] INTESTINAL NEURAMINIDASE ACTIVITY OF SUCKLING RATS AND OTHER MAMMALS - RELATIONSHIP TO SIALIC-ACID CONTENT OF MILK [J].

DICKSON, JJ ;

MESSER, M .

BIOCHEMICAL JOURNAL, 1978, 170 (02) :407-413

[5] ISOLATION OF MICROVILLUS PLASMA-MEMBRANES FROM SUCKLING-RAT INTESTINE - INFLUENCE OF PREMATURE INDUCTION OF DIGESTIVE ENZYMES BY INJECTION OF CORTISOL ACETATE [J].

GALAND, G ;

FORSTNER, GG .

BIOCHEMICAL JOURNAL, 1974, 144 (02) :293-+

[6] INTESTINAL BETA-GALACTOSIDASES .1. SEPARATION AND CHARACTERIZATION OF 3 ENZYMES IN NORMAL HUMAN INTESTINE [J].

GRAY, GM ;

SANTIAGO, NA .

JOURNAL OF CLINICAL INVESTIGATION, 1969, 48 (04) :716-&

[7]

GRAY GM, 1983, METABOLIC BASIS INHE, P1729

[8] ALKALINE-PHOSPHATASE OF BASAL LATERAL AND BRUSH-BORDER PLASMA-MEMBRANES FROM INTESTINAL EPITHELIUM [J].

HANNA, SD ;

MIRCHEFF, AK ;

WRIGHT, EM .

JOURNAL OF SUPRAMOLECULAR STRUCTURE, 1979, 11 (04) :451-466

[9] SUGAR MALABSORPTION DUE TO DEFICIENCIES OF DISACCHARIDASE ACTIVITIES AND OF MONOSACCHARIDE TRANSPORT [J].

HOLZEL, A .

ARCHIVES OF DISEASE IN CHILDHOOD, 1967, 42 (224) :341-+

[10] COMPARATIVE BIOCHEMICAL STUDIES OF MILKS .2. DIALYZABLE CARBOHYDRATES [J].

JENNESS, R ;

REGEHR, EA ;

SLOAN, RE .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1964, 13 (04) :339-&

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