MODULATION OF CLOSTRIDIUM-DIFFICILE INDUCED MORTALITY AS A FUNCTION OF THE DOSE AND THE VIABILITY OF THE SACCHAROMYCES-BOULARDII USED AS A PREVENTATIVE AGENT IN GNOTOBIOTIC MICE

被引：26

作者：

ELMER, GW ^{[1
]}

CORTHIER, G ^{[1
]}

机构：

[1] INRA,CTR RECH JOUY EN JOSAS,ECOL & PHYSIOL SYST DIGEST LAB,F-78350 JOUY EN JOSAS,FRANCE

来源：

CANADIAN JOURNAL OF MICROBIOLOGY | 1991年 / 37卷 / 04期

关键词：

SACCHAROMYCES-BOULARDII; CLOSTRIDIUM-DIFFICILE; COLITIS; PSEUDOMEMBRANOUS COLITIS; GNOTOBIOTIC MICE;

D O I：

10.1139/m91-049

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ability of viable and nonviable Saccharomyces boulardii to protect gnotobiotic mice from Clostridium difficile induced mortality was tested. With the exception of irradiated S. boulardii, which retained some activity, only viable yeast protected the mice from lethality. The survival of C. difficile infected mice was dependent on the dose of the yeast provided in the drinking water.

引用

页码：315 / 317

页数：3

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