UNUSUAL MOLECULAR CHARACTERISTICS OF A REPEAT SEQUENCE ISLAND WITHIN A GIEMSA-POSITIVE BAND ON THE MOUSE X-CHROMOSOME

被引：31

作者：

NASIR, J

FISHER, EMC

BROCKDORFF, N

DISTECHE, CM

LYON, MF

BROWN, SDM

机构：

[1] UNIV WASHINGTON,DEPT PATHOL,SEATTLE,WA 98195

[2] MRC,RADIOBIOL UNIT,DIDCOT OX11 0RD,OXON,ENGLAND

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1990年 / 87卷 / 01期

关键词：

CpG islands; Long interspersed repeats;

D O I：

10.1073/pnas.87.1.399

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The mouse genome contains 50 copies of a long complex repeat unit localized as a repeat sequence island to the A3 Giemsa-positive (dark) band on the mouse X chromosome. The repeat units are not tandemly arranged but are taxtaposed and inserted by unrelated sequences of high repetition. The repeat sequence island possesses two notable features that have been suggested as diagnostic features of mamalian Giemsa-positive bands. First, the repeat sequence island encompasses a 1-megabase region devoid of CpG islands; second, it features a high concentration of L1 long interspersed repeat sequences.

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页码：399 / 403

页数：5

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