RECTAL ENDOSONOGRAPHY ACCURATELY PREDICTS DEPTH OF PENETRATION IN RECTAL-CANCER

被引:20
作者
BEYNON, J
MORTENSEN, NJM
CHANNER, JL
RIGBY, H
机构
[1] Department of Surgery, Wrexham Maelor Hospital, Wrexham
[2] Department of Surgery, John Radcliffe Hospital, Oxford
[3] Department of Pathology, Bristol Royal Infirmary, Oxford
关键词
D O I
10.1007/BF01647651
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Sixty-three patients with primary rectal adenocarcinomas have been examined prior to surgery with rectal endosonography (ES). Maximum depths of tumour penetration measured endosonographically have been compared with subsequent maximum depths measured on the fixed resected specimen (n = 30) and the histological slide (n = 61). In both cases there was a good degree of correlation between the ultrasonic estimations of depth and the histological ones (r = 0.36, p = 0.05. CI = 95% and r = 0.46, p < 0.001, CI = 99% respectively). In 12 cases ultrasonic depths of tumour were also measured in the laboratory and then compared with depths from fixed (n = 12) and fresh specimens (n = 5) with a good correlation (r = 0.75, p = 0.005, CI = 99% and r = 0.79, p = 0.036, CI = 95% respectively). Rectal endosonographic estimation of rectal cancer depth of invasion is an accurate measure of tumour penetration and may help distinguish between fixation due to inflammatory tissue and tumour fixity.
引用
收藏
页码:4 / 7
页数:4
相关论文
共 27 条
[1]  
Dukes C.E., Bussey H.J.R., The spread of rectal cancer and its effect on prognosis, Br J Cancer, 12, pp. 309-320, (1985)
[2]  
Wood C.B., Ratcliffe J.G., Burt TW.ET, Malcolm A.J.H., Blumgart L.H., Local tumour invasion as a prognostic factor in colorectal carcinoma, Br J Surg, 68, pp. 326-328, (1981)
[3]  
Gunderson L.L., Sosin H., Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum, Cancer, 34, pp. 1278-1292, (1974)
[4]  
Moosa A.R., Ree P.C., Marks J.E., Levin B., Platz C.E., Skinner D.B., Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum and rectosigmoid, British Journal of Surgery, 62, pp. 727-730, (1975)
[5]  
Godwin J.C., Brown C.C., Some prognostic factors in survival of patients with cancer of the colon and rectum, J Chronic Dis, 28, pp. 441-454, (1975)
[6]  
Quirke P., Durdey P., Dixon M.F., Williams N.S., Lancet, pp. 996-998, (1986)
[7]  
Habib N.A., Peck M.A., Sawyer C.N., Blaxland J.W., Luck R.J., Does fixity affect prognosis in colorectal tumours?, Br J Surg, 70, pp. 423-424, (1983)
[8]  
Dragsted J., Gammelgaard J., Endoluminal ultrasonic scanning in the evaluation of rectal cancer, Gastrointest Radiol, 8, pp. 367-369, (1983)
[9]  
Hildebrandt U., Fiefel G., Pre-operative staging of rectal cancer by intrarectal ultrasound, Dis Colon Rectum, 28, pp. 42-46, (1985)
[10]  
Saitoh N., Okui K., Sarashina H., Suzuki M., Arai T., Nunomura M., Evaluation of echographic diagnosis of rectal cancer using intrarectal ultrasonic examination, Dis Colon Rectum, 29, pp. 234-242, (1986)