CHIRAL ALPHA-HYDROXY-AND ALPHA,BETA-DIHYDROXY-ALDEHYDES FROM D-ISOASCORBIC AND L-ASCORBIC ACIDS - USEFUL PRECURSORS FOR THE SYNTHESIS OF FATTY-ACID METABOLITES

被引：35

作者：

LEMERRER, Y

GRAVIERPELLETIER, C

DUMAS, J

DEPEZAY, JC

机构：

[1] Université René Descartes, Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiquas, Unité Associée au CNRS, 75270 Paris Cedex 06

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)94414-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The four possible stereoisomers of α,β-dihydroxyaldehydes, useful building blocks for the synthesis of fatty acids metabolites, are synthesized via epoxy-tetrols derived from D-isoascorbic and L-ascorbic acids. The general method we develop allows the synthesis of chiral α-hydroxyaldehydes as well. © 1990.

引用

页码：1003 / 1006

页数：4

共 23 条

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