PNEUMOCOCCAL VACCINATION IN CHILDREN WITH ACUTE LYMPHOCYTIC-LEUKEMIA

被引：9

作者：

FELDMAN, S

MALONE, W

WILBUR, R

SCHIFFMAN, G

机构：

[1] ST JUDE CHILDRENS RES HOSP, DIV INFECT DIS, 332 N LAUDERDALE, MEMPHIS, TN 38101 USA

[2] SUNY DOWNSTATE MED CTR, DEPT MICROBIOL & IMMUNOL, BROOKLYN, NY 11203 USA

来源：

MEDICAL AND PEDIATRIC ONCOLOGY | 1985年 / 13卷 / 02期

关键词：

D O I：

10.1002/mpo.2950130205

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Children (63) with acute lymphocytic leukemia and treated according to a standard therapy protocol were immunized with the 14-valent pneumococcal vaccine. Forty six children were vaccinated 1, 3 or 6 mo. following initial induction remission; 15 were vaccinated 4-6 wk following successful completion of 30 mo. or antileukemia therapy; and 2 were vaccinated at the time of diagnosis. Response to the vaccine was suboptimal and by the 6-mo. follow-up there were only 2 serotypes for which > 1/2 the patients tested had .gtoreq. 300 ng antibodies N/ml.

引用

页码：69 / 72

页数：4

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