GENETIC-ACTIVITY OF THE HUMAN CARCINOGEN SULFUR MUSTARD TOWARDS SALMONELLA AND THE MOUSE BONE-MARROW

被引：27

作者：

ASHBY, J

TINWELL, H

CALLANDER, RD

CLARE, N

机构：

[1] ICI Central Toxicology Laboratory, Macclesfield,, Ches. Ches. SK10 4TJ, Alderley Park

来源：

MUTATION RESEARCH | 1991年 / 257卷 / 03期

关键词：

SULFUR MUSTARD; GENOTOXICITY; SALMONELLA; MOUSE BONE MARROW;

D O I：

10.1016/0165-1110(91)90004-F

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Sulphur mustard is clearly mutagenic to the repair-proficient (uvrB+) strain G46 of S. typhimurium. It is also a micronucleus-inducing agent to the mouse bone marrow. These data strengthen the database indicating that most human carcinogens are genotoxic.

引用

页码：307 / 311

页数：5

共 30 条

[1] THE PRESENT LACK OF EVIDENCE FOR UNIQUE RODENT GERM-CELL MUTAGENS
ADLER, ID
ASHBY, J
[J]. MUTATION RESEARCH, 1989, 212 (01): : 55 - 66
[2] WEAK MUTAGENICITY TO SALMONELLA OF THE FORMALDEHYDE-RELEASING ANTI-TUMOR AGENT HEXAMETHYLMELAMINE
ASHBY, J
CALLANDER, RD
ROSE, FL
[J]. MUTATION RESEARCH, 1985, 142 (03): : 121 - 125
[3] REEVALUATION OF THE NEED FOR MULTIPLE SAMPLING TIMES IN THE MOUSE BONE-MARROW MICRONUCLEUS ASSAY - RESULTS FOR DMBA
ASHBY, J
MIRKOVA, E
[J]. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 1987, 10 (03) : 297 - 305
[4] MUTAGENICITY TO BACTERIA, CULTURED-CELLS, AND RODENTS OF THE HUMAN CARCINOGEN CHLORNAPHAZINE
ASHBY, J
LOQUET, C
ISHIDATE, M
CALLANDER, RD
ALBANESE, R
[J]. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 1988, 12 (04) : 365 - 374
[5] Auerbach C., 1947, PROC ROY SOC EDINBURGH, V62B, P271
[6] Production of mutations by allyl isothiocyanate
Auerbach, C
Robson, JM
[J]. NATURE, 1944, 154 : 81 - 81
[7] The modifying influence of dichloroethyl sulphide on the induction of tumours in mice by tar.
Berenblum, I
[J]. JOURNAL OF PATHOLOGY AND BACTERIOLOGY, 1929, 32 (03): : 425 - 434
[8] REACTION OF MONO- AND DI-FUNCTIONAL ALKYLATING AGENTS WITH NUCLEIC ACIDS
BROOKES, P
LAWLEY, PD
[J]. BIOCHEMICAL JOURNAL, 1961, 80 (03) : 496 - &
[9] GENETIC TOXICOLOGY OF NITROGEN AND SULFUR MUSTARD
FOX, M
SCOTT, D
[J]. MUTATION RESEARCH, 1980, 75 (02): : 131 - 168
[10] USE OF REC- BACTERIA FOR TESTING OF CARCINOGENIC SUBSTANCES
ICHINOTSUBO, D
MOWER, HF
SETLIFF, J
MANDEL, M
[J]. MUTATION RESEARCH, 1977, 46 (02): : 53 - 61

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