GENE FOR 17-ALPHA-HYDROXYLASE/C (17-20) LYASE P-450 - COMPLETE NUCLEOTIDE-SEQUENCE OF THE PORCINE GENE AND 5' UPSTREAM SEQUENCE OF THE RAT GENE

被引:16
作者
ZHANG, PL [1 ]
NASON, TF [1 ]
HAN, XG [1 ]
HALL, PF [1 ]
机构
[1] PRINCE WALES HOSP, DEPT ENDOCRINOL, RANDWICK, NSW 2031, AUSTRALIA
关键词
17-ALPHA-HYDROXYLASE; NUCLEOTIDE SEQUENCE; (PIG); (RAT);
D O I
10.1016/0167-4781(92)90039-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We describe the isolation and characterization of a full-length clone for the porcine 17-alpha-hydroxylase/C(17-20) lyase (CYP17) gene. The complete exon and partial intron sequences are presented including approx. 1000 bp of the 5' upstream sequence. In addition we describe the isolation and characterization of the 5' upstream region of the rat CYP17 gene. The sequences of the first exon, part of the first intron, and approx. 3.5 kb of the 5' upstream region are presented.
引用
收藏
页码:345 / 348
页数:4
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