SIGNAL SEQUENCE MUTATIONS DISRUPT FEEDBACK BETWEEN SECRETION OF AN EXPORTED PROTEIN AND ITS SYNTHESIS IN ESCHERICHIA-COLI

被引：48

作者：

KUMAMOTO, CA ^{[1
]}

OLIVER, DB ^{[1
]}

BECKWITH, J ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DEPT MICROBIOL & MOLEC GENET,BOSTON,MA 02115

来源：

NATURE | 1984年 / 308卷 / 5962期

关键词：

D O I：

10.1038/308863a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：863 / 864

页数：2

共 14 条

[1]

BASSFORD P, 1979, NATURE, V277, P538, DOI 10.1038/277538a0

[2] MUTATIONS WHICH ALTER THE FUNCTION OF THE SIGNAL SEQUENCE OF THE MALTOSE BINDING-PROTEIN OF ESCHERICHIA-COLI [J].

BEDOUELLE, H ;

BASSFORD, PJ ;

FOWLER, AV ;

ZABIN, I ;

BECKWITH, J ;

HOFNUNG, M .

NATURE, 1980, 285 (5760) :78-81

[3] FLUOROGRAPHIC DETECTION OF RADIOACTIVITY IN POLYACRYLAMIDE GELS WITH THE WATER-SOLUBLE FLUOR, SODIUM-SALICYLATE [J].

CHAMBERLAIN, JP .

ANALYTICAL BIOCHEMISTRY, 1979, 98 (01) :132-135

[4]

DEBARBOUILLE M, 1978, J MOLEC BIOL, V114, P59

[5] SUPPRESSOR MUTATIONS THAT RESTORE EXPORT OF A PROTEIN WITH A DEFECTIVE SIGNAL SEQUENCE [J].

EMR, SD ;

HANLEYWAY, S ;

SILHAVY, TJ .

CELL, 1981, 23 (01) :79-88

[6]

HALL M, 1982, ANNLS MICROBIOL I A, V133, P112

[7] PROTEIN LOCALIZATION IN ESCHERICHIA-COLI - IS THERE A COMMON STEP IN THE SECRETION OF PERIPLASMIC AND OUTER-MEMBRANE PROTEINS [J].

ITO, K ;

BASSFORD, PJ ;

BECKWITH, J .

CELL, 1981, 24 (03) :707-717

[8] A TEMPERATURE-SENSITIVE MUTANT OF ESCHERICHIA-COLI EXHIBITING SLOW PROCESSING OF EXPORTED PROTEINS [J].

ITO, K ;

WITTEKIND, M ;

NOMURA, M ;

SHIBA, K ;

YURA, T ;

MIURA, A ;

NASHIMOTO, H .

CELL, 1983, 32 (03) :789-797

[9] ACTIVE-TRANSPORT OF MALTOSE IN ESCHERICHIA-COLI-K12 - INVOLVEMENT OF A PERIPLASMIC MALTOSE BINDING-PROTEIN [J].

KELLERMANN, O ;

SZMELCMAN, S .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1974, 47 (01) :139-149

[10] MUTATIONS IN A NEW GENE, SECB, CAUSE DEFECTIVE PROTEIN LOCALIZATION IN ESCHERICHIA-COLI [J].

KUMAMOTO, CA ;

BECKWITH, J .

JOURNAL OF BACTERIOLOGY, 1983, 154 (01) :253-260

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