HUMAN NEUTROPHIL AZUROCIDIN SYNERGIZES WITH LEUKOCYTE ELASTASE AND CATHEPSIN-G IN THE KILLING OF CAPNOCYTOPHAGA-SPUTIGENA

被引：23

作者：

MIYASAKI, KT ^{[1
]}

BODEAU, AL ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,SCH DENT,INST DENT RES,LOS ANGELES,CA 90024

来源：

INFECTION AND IMMUNITY | 1992年 / 60卷 / 11期

关键词：

D O I：

10.1128/IAI.60.11.4973-4975.1992

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Azurocidin was purified in the presence of phenylmethylsulfonyl fluoride. Electrophoresis revealed at least seven species which exhibited N-terminal sequences consistent with azurocidin. Azurocidin exhibited no bactericidal activity against Capnocytophaga sputigena or other oral bacteria but synergized the bactericidal activity of enzymatically active elastase. Azurocidin also interacted synergistically with cathepsin G.

引用

页码：4973 / 4975

页数：3

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