EVIDENCE FROM MULTIPLE ISOTOPE EFFECT DETERMINATIONS FOR COUPLED HYDROGEN MOTION AND TUNNELING IN THE REACTION CATALYZED BY GLUCOSE-6-PHOSPHATE-DEHYDROGENASE

被引：51

作者：

HERMES, JD ^{[1
]}

CLELAND, WW ^{[1
]}

机构：

[1] UNIV WISCONSIN,DEPT BIOCHEM,MADISON,WI 53706

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1984年 / 106卷 / 23期

关键词：

D O I：

10.1021/ja00335a077

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：7263 / 7264

页数：2

共 12 条

[1] MECHANISTIC DEDUCTIONS FROM ISOTOPE EFFECTS IN MULTIREACTANT ENZYME MECHANISMS [J].

COOK, PF ;

CLELAND, WW .

BIOCHEMISTRY, 1981, 20 (07) :1790-1796

[2] PRIMARY AND SECONDARY DEUTERIUM-ISOTOPE EFFECTS ON EQUILIBRIUM-CONSTANTS FOR ENZYME-CATALYZED REACTIONS [J].

COOK, PF ;

BLANCHARD, JS ;

CLELAND, WW .

BIOCHEMISTRY, 1980, 19 (21) :4853-4858

[3] SECONDARY DEUTERIUM AND N-15 ISOTOPE EFFECTS IN ENZYME-CATALYZED REACTIONS - CHEMICAL MECHANISM OF LIVER ALCOHOL-DEHYDROGENASE [J].

COOK, PF ;

OPPENHEIMER, NJ ;

CLELAND, WW .

BIOCHEMISTRY, 1981, 20 (07) :1817-1825

[4] USE OF MULTIPLE ISOTOPE EFFECTS TO DETERMINE ENZYME MECHANISMS AND INTRINSIC ISOTOPE EFFECTS - MALIC ENZYME AND GLUCOSE-6-PHOSPHATE-DEHYDROGENASE [J].

HERMES, JD ;

ROESKE, CA ;

OLEARY, MH ;

CLELAND, WW .

BIOCHEMISTRY, 1982, 21 (20) :5106-5114

[5]

HERMES JD, BIOCHEMISTRY

[6] REACTION-COORDINATE TUNNELING IN HYDRIDE-TRANSFER REACTIONS [J].

HUSKEY, WP ;

SCHOWEN, RL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (17) :5704-5706

[7] PRIMARY KINETIC HH HD DH DD ISOTOPE EFFECTS AND PROTON TUNNELLING IN DOUBLE PROTON-TRANSFER REACTIONS [J].

LIMBACH, HH ;

HENNIG, J ;

GERRITZEN, D ;

RUMPEL, H .

FARADAY DISCUSSIONS, 1982, 74 :229-243

[8] ISOTOPE EFFECTS ON HYDRIDE TRANSFER BETWEEN NAD+ ANALOGS [J].

OSTOVIC, D ;

ROBERTS, RMG ;

KREEVOY, MM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (26) :7629-7631

[9] CONTRIBUTION OF TUNNELING TO SECONDARY ISOTOPE EFFECTS IN PROTON-TRANSFER REACTIONS [J].

SAUNDERS, WH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (07) :2223-2224

[10]

Schowen R. L, 1978, TRANSIT STATES BIOCH, P225

← 1 2 →