AN INTRAMOLECULAR ADDITION-ELIMINATION STRATEGY FOR THE SYNTHESIS OF CARBAPENEMS

被引：10

作者：

ZIEGLER, CB

CURRAN, WV

FEIGELSON, GB

BITHA, P

FABIO, P

STROHMEYER, T

SHORT, K

LIN, YI

机构：

[1] Medical Research Division, American Cyanamid Company, Lederle Laboratories, Pearl River

来源：

TETRAHEDRON | 1994年 / 50卷 / 42期

关键词：

D O I：

10.1016/S0040-4020(01)89561-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 2-[(4-fluorophenylsulfonyl)methyl] carbapenem carboxylate 20 is described. The key step is a base mediated addition-elimination ring closure of a iodovinyl sulfone 12.

引用

页码：12085 / 12096

页数：12

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