ANTIMICROBIAL METABOLITES FROM A BACTERIAL SYMBIONT

被引：83

作者：

LI, JX ^{[1
]}

CHEN, GH ^{[1
]}

WEBSTER, JM ^{[1
]}

CZYZEWSKA, E ^{[1
]}

机构：

[1] SIMON FRASER UNIV,DEPT CHEM,VANCOUVER,BC V5A 1S6,CANADA

来源：

JOURNAL OF NATURAL PRODUCTS-LLOYDIA | 1995年 / 58卷 / 07期

关键词：

D O I：

10.1021/np50121a016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two types of antibiotics, namely, indoles and dithiolopyrrolones, have been isolated and identified from Xenorhabdus bovienii A2. Compounds 1 and 2 showed strong activity against Cryptococcus neoformans, compounds 3 and 4 showed strong activity against Botrytis cinerea, and compounds 1, 3, and 4 showed significant activity against Phytophthora infestans (2 was nor tested). In addition, two lower homologues of xenorhabdins 5 and 6, namely, 6-(N-3'-methylbutanamido)-[4,5-dihydro-1,2-dithiolo[4,3-b]pyrrol-5-one [7] and 6-(N-butanamido)[4,5-dihydro-1 ,2-dithiolo[4,3-b]pyrrol-5-one [8], have been isolated and characterized for the first time.

引用

页码：1081 / 1086

页数：6

共 17 条

[1]

Akhurst R., 2012, PARASITES PATHOGENS, P1

[2]

AKHURST RJ, 1982, J GEN MICROBIOL, V128, P3061

[3] TAXONOMIC STUDY OF XENORHABDUS, A GENUS OF BACTERIA SYMBIOTICALLY ASSOCIATED WITH INSECT PATHOGENIC NEMATODES [J].