NUCLEOPHILIC-ATTACK AT THE CENTRAL CARBON-ATOM OF (PI-ALLYL)PALLADIUM COMPLEXES - FORMATION OF ALPHA-CYCLOPROPYL ESTERS

被引：70

作者：

HOFFMANN, HMR

OTTE, AR

WILDE, A

机构：

[1] Institut Für Organische Chemie, Universität Hannover, D-W-3000

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH | 1992年 / 31卷 / 02期

关键词：

D O I：

10.1002/anie.199202341

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Distinctly higher yields of functionalized cyclopropanes such as 1 can be achieved when 1,2-bis(dimethylamino)ethane, followed by CO, are added to the reaction of pi-allylpalladium complexes with lithium enolates of esters. The usual, energetically favored allylic alkylation is efficiently suppressed in this way. The role of the amine ligands is crucial: addition of 1,2-bis(dimethylamino)methane produces no cyclopropanation product; with sparteine only low yields are obtained.

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页码：234 / 236

页数：3

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