ACETYLSALICYLIC-ACID VS METOPROLOL IN MIGRAINE PROPHYLAXIS - A DOUBLE-BLIND CROSS-OVER STUDY

被引：25

作者：

GROTEMEYER, KH ^{[1
]}

SCHARAFINSKI, HW ^{[1
]}

SCHLAKE, HP ^{[1
]}

HUSSTEDT, IW ^{[1
]}

机构：

[1] ST JOSEPHS HOSP,DEPT NEUROL,MORS,GERMANY

来源：

HEADACHE | 1990年 / 30卷 / 10期

关键词：

D O I：

10.1111/j.1526-4610.1990.hed3010639.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

SYNOPSIS In a double blind cross‐over study, 28 patients, 5 male and 23 female, aged 31 ± 14 years, after a run‐in period of 8 weeks, were treated for 3 months with acetylsalicylic acid and for another 3 months with metoprolol, both in a prophylactic mode. Attack frequency was reduced significantly with both therapeutic regimens (ASA p<0.001, metoprolol p<0.00005). Reduction of attacks below 50% was seen with metoprolol in 14 cases, and with ASA in three cases. Even though ASA was of statistically significant efficacy in migraine prophylaxis, it clearly is not the drug of first choice in migraine prophylaxis. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：639 / 641

页数：3

共 21 条

[1]

ANDERSSON PG, 1982, CEPHALALGIA, V2, P207

[2] PROPRANOLOL AND ACETYLSALICYLIC-ACID IN MIGRAINE PROPHYLAXIS - DOUBLE-BLIND CROSSOVER STUDY [J].