SILVER SULFADIAZINE-INDUCED HEMOLYTIC-ANEMIA IN A GLUCOSE-6-PHOSPHATE DEHYDROGENASE-DEFICIENT BURN PATIENT

被引：20

作者：

ELDAD, A

NEUMAN, A

WEINBERG, A

BENMEIR, P

ROTEM, M

WEXLER, MR

机构：

来源：

BURNS | 1991年 / 17卷 / 05期

关键词：

D O I：

10.1016/S0305-4179(05)80083-X

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A 20-year-old soldier sustained 35 per cent body surface area burns by open flames. He was treated with topical application of 1 per cent silver sulphadiazine (SSD) twice daily. Four days postburn he developed acute haemolytic anaemia. Withdrawal of SSD was followed by complete recovery. A glucose-6-phosphate dehydrogenase (G6PD) deficiency was proven by pathological Motulski tests. Although the hazards of SSD are well indicated by the manufacturers, there appear to be no written reports of haemolysis induced by this drug in G6PD-deficient patients.

引用

页码：430 / 432

页数：3