SYNTHESIS OF (7R)-7H-INDOLO[3,4-GH][1,4]BENZOXAZINES - A NEW CLASS OF D-HETEROERGOLINES WITH DOPAMINE AGONIST ACTIVITY

被引：22

作者：

ANDERSON, PS ^{[1
]}

BALDWIN, JJ ^{[1
]}

MCCLURE, DE ^{[1
]}

LUNDELL, GF ^{[1
]}

JONES, JH ^{[1
]}

RANDALL, WC ^{[1
]}

MARTIN, GE ^{[1
]}

WILLIAMS, M ^{[1
]}

HIRSHFIELD, JM ^{[1
]}

CLINESCHMIDT, BV ^{[1
]}

LUMMA, PK ^{[1
]}

REMY, DC ^{[1
]}

机构：

[1] MERCK SHARP & DOHME,RES LABS,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1983年 / 26卷 / 03期

关键词：

D O I：

10.1021/jm00357a010

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：363 / 367

页数：5

共 18 条

[1] A NEW CLASS OF D-HETEROERGOLINES - TOTAL SYNTHESIS AND RESOLUTION OF A 9-OXAERGOLINE, 4,6,6A,8,9,10A-HEXAHYDRO-7-ETHYL-7H-INDOLO[3,4-GH][1,4]BENZOXAZINE [J].

ANDERSON, PS ;

BALDWIN, JJ ;

MCCLURE, DE ;

LUNDELL, GF ;

JONES, JH .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (11) :2184-2187

[2]

BOWMAN RE, 1973, J CHEM SOC P1, P483

[3]

CALNE DB, 1974, LANCET, V2, P1355

[4] RIGID CONGENERS OF DOPAMINE BASED ON OCTAHYDROBENZO[F]QUINOLINE - PERIPHERAL AND CENTRAL EFFECTS [J].

CANNON, JG ;

SUAREZGUTIERREZ, C ;

LEE, T ;

LONG, JP ;

COSTALL, B ;

FORTUNE, DH ;

NAYLOR, RJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (04) :341-347

[5] ERGOT ALKALOIDS - SYNTHESIS OF 6-ALKYL-8-ERGOLENES AND 6-METHYL-8-AMINOERGOLINES AS POTENTIAL PROLACTIN INHIBITORS [J].

CRIDER, AM ;

ROBINSON, JM ;

FLOSS, HG ;

CASSADY, JM ;

CLEMENS, JA .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (11) :1473-1477

[6] NUCLEAR MAGNETIC-RESONANCE ENANTIOMER REAGENTS - CONFIGURATIONAL CORRELATIONS VIA NUCLEAR MAGNETIC-RESONANCE CHEMICAL-SHIFTS OF DIASTEREOMERIC MANDELATE, O-METHYLMANDELATE, AND ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETATE (MTPA) ESTERS [J].

DALE, JA ;

MOSHER, HS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (02) :512-519

[7]

GOPINATHAN G, 1981, NEUROLOGY, V31, P371

[8]

JOHNSON CK, 1965, ORNL3794 REP

[9] MULTIPLE RECEPTORS FOR DOPAMINE [J].

KEBABIAN, JW ;

CALNE, DB .

NATURE, 1979, 277 (5692) :93-96

[10]

KONIG JFR, 1973, RAT BRAIN

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