Perinatal Autopsy Evaluation of 2150 Autopsies in the Cukurova Region of Turkey

被引:6
作者
Acikalin, Arbil [1 ]
Kilic Bagir, Emine [1 ]
Torun, Goncagul [1 ]
Totan Ates, Berna [1 ]
Erdogan, Seyda [1 ]
Uguz, Aysun [1 ]
Ergin, Melek [1 ]
Buyukkurt, Selim [2 ]
Tuncay Ozgunen, Fatma [2 ]
Tunali, Nurdan [1 ]
Gumurdulu, Derya [1 ]
机构
[1] Cukurova Univ, Fac Med, Dept Pathol, Adana, Turkey
[2] Cukurova Univ, Fac Med, Dept Obstet & Gynecol, Adana, Turkey
关键词
Autopsy; Congenital abnormalities; Prenatal diagnosis; Perinatal mortality; Syndrome;
D O I
10.5146/tjpath.2014.01266
中图分类号
R36 [病理学];
学科分类号
100104 [病理学与病理生理学];
摘要
Objective: We aimed to document the reasons of perinatal deaths in a large autopsy series performed in our institute, which is a reference center in the Cukurova region of Turkey. Material and Method: The study included 2150 autopsies performed between January 2000 and December 2012at our institute. Diagnoses were categorized according to the detected pathologies; congenital malformations were detailed based on systems. Results: A pathology was detected in 1619 of 2150 (73.3%) autopsies. Congenital malformations were the most common diagnosis with 68.2%. Neural tube defects and central nervous system malformations were the most frequent system malformation in 28.8% of cases, followed by the urogenital system (11.4%) and musculoskeletal system (8.3%), respectively. Malformation syndromes including multisystem anomalies were defined in 109 cases (9.3%). Conclusion: Congenital malformations are the most common reason for perinatal deaths, with autopsy having an additive role to prenatal and genetic evaluations and providing foresight for planning a subsequent pregnancy.
引用
收藏
页码:189 / 194
页数:6
相关论文
共 11 条
[1]
Congenital Malformations in Perinatal Autopsies - A Study of 100 Cases [J].
Andola, Uma S. ;
Anita, A. M. ;
Ahuja, Mukta ;
Anekla, Sainath K. .
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2012, 6 (10) :1726-1730
[2]
Evaluation of 2407 fetuses in a Turkish population [J].
Ceylaner, Guelay ;
Ceylaner, Serdar ;
Guenyeli, Ilker ;
Ekici, Eyuep ;
Celasun, Buelent ;
Danisman, Nuri .
PRENATAL DIAGNOSIS, 2007, 27 (09) :800-807
[3]
Value of perinatal autopsy [J].
Faye-Petersen, OM ;
Guinn, DA ;
Wenstrom, KD .
OBSTETRICS AND GYNECOLOGY, 1999, 94 (06) :915-920
[4]
Giordano G, 2011, Acta Biomed, V82, P230
[5]
Congenital malformations in Shimla [J].
Grover N. .
The Indian Journal of Pediatrics, 2000, 67 (4) :249-251
[6]
Evaluation of Fetal Autopsy Findings in the Hatay Region: 274 Cases [J].
Hakverdi, Sibel ;
Guzelmansur, Ismail ;
Gungoren, Arif ;
Toprak, Serhat ;
Yaldiz, Mehmet ;
Hakverdi, Ali Ulvi .
TURKISH JOURNAL OF PATHOLOGY, 2012, 28 (02) :154-161
[7]
Kalyani R, 2013, J Indian Med Assoc, V111, P89
[8]
Lawn J, 2005, B WORLD HEALTH ORGAN, V83, P409
[9]
Cardiac findings in routine fetal autopsies: more than meets the eye? [J].
Ramalho, Carla ;
Brandao, Otilia ;
Monterroso, Jose ;
Matias, Alexandra ;
Montenegro, Nuno .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2012, 163 (02) :142-147
[10]
Clinical utility of fetal autopsy and comparison with prenatal ultrasound findings [J].
Sankar, V. H. ;
Phadke, S. R. .
JOURNAL OF PERINATOLOGY, 2006, 26 (04) :224-229