ASSESSMENT OF THE RESPONSE TO CHEMOTHERAPY IN ESOPHAGEAL CANCER

被引:14
作者
WALKER, SJ [1 ]
ALLEN, SM [1 ]
STEEL, A [1 ]
CULLEN, MH [1 ]
MATTHEWS, HR [1 ]
机构
[1] E BIRMINGHAM DIST GEN HOSP,REG DEPT THORAC SURG,OESOPHAGEAL RES LAB,BIRMINGHAM B9 5ST,W MIDLANDS,ENGLAND
关键词
ESOPHAGEAL CANCER; CHEMOTHERAPY; SURGERY;
D O I
10.1016/1010-7940(91)90104-R
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thirty-eight patients with localised oesophageal carcinoma have been studied by computed tomography (CT) and barium swallow before and after preoperative chemotherapy and the results correlated with the pathological findings in the resected specimen. Overall 48% of patients showed a complete or partial response to chemotherapy on CT, compared with 50% on barium and 94% on pathological examination. This study highlights deficiencies in CT scanning and barium swallow as methods of assessing the regression of tumor bulk following chemotherapy for oesophageal carcinoma. We suggest that strict and specific criteria will have to be laid down before the results of chemotherapy in this disease can be reliably and accurately evaluated.
引用
收藏
页码:519 / 522
页数:4
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