SPONTANEOUS REGRESSION IN MERKEL CELL (NEUROENDOCRINE) CARCINOMA OF THE SKIN

被引：63

作者：

KAYASHIMA, K

ONO, T

JOHNO, M

KOJO, Y

YAMASHITA, N

MATSUNAGA, W

机构：

[1] KUMAMOTO CITY HOSP,DIV RECONSTRUCT PLAST SURG,KUMAMOTO,JAPAN

[2] KUMAMOTO CITY HOSP,DIV DERMATOL,KUMAMOTO,JAPAN

来源：

ARCHIVES OF DERMATOLOGY | 1991年 / 127卷 / 04期

关键词：

D O I：

10.1001/archderm.127.4.550

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

In two Japanese women, 68 and 88 years old, Merkel cell (neuroendocrine) carcinoma of the face developed. Their tumors regressed after biopsy was performed, a rare occurrence. Histological and electron microscopic examination showed apoptosis, cellular necrosis, and an infiltration composed mainly of lymphocytes in the tumors. These changes may have been related to the mechanism of regression. It is interesting that our two patients were women, as was another patient described with Merkel cell carcinoma regression, in light of the fact that the prognosis of this tumor is sex dependent.

引用

页码：550 / 553

页数：4

共 9 条

[1]

CURSON C, 1979, J CUTAN PATHOL, V6, P432, DOI 10.1111/j.1600-0560.1979.tb01166.x

[2]

GOEPFERT H, 1984, ARCH OTOLARYNGOL, V110, P707

[3] NEURO-ENDOCRINE (MERKEL CELL) CARCINOMA OF THE SKIN - ITS NATURAL-HISTORY, DIAGNOSIS, AND TREATMENT [J].