EXPRESSION OF GENETIC AND ENVIRONMENTAL VARIATION DURING AGING .2. SELECTION FOR INCREASED LIFE-SPAN IN DROSOPHILA-MELANOGASTER

被引：26

作者：

ENGSTROM, G

LILJEDAHL, LE

BJORKLUND, T

机构：

[1] Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala, S-750 07

来源：

THEORETICAL AND APPLIED GENETICS | 1992年 / 85卷 / 01期

关键词：

GENETIC AND ENVIRONMENTAL VARIATION; AGE CHANGES; SELECTION FOR LONGEVITY;

D O I：

10.1007/BF00223841

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

A selection experiment with Drosophila melanogaster was carried out to test some theories of ageing by calculating genetic parameters for a reproductive fitness trait at different ages. Successful selection for increased lifespan showed that longevity is a trait under genetic control. Positive genetic correlations between early and late fitness were found. These results do not support the pleiotropy theory of ageing which predicts a negative genetic correlation. Both environmental and additive genetic variation clearly increased with age. Increased environmental variation probably reflects the individuals' difficulties in coping with environmental stress. The increase in additive genetic variation supports the mutation accumulation theory of ageing, as welt as other theories that postulate increased additive genetic variation with age.

引用

页码：26 / 32

页数：7

共 24 条

[1]

[Anonymous], 1952, UNSOLVED PROBLEM BIO

[2] SUCCESSFUL SELECTION FOR INCREASED LONGEVITY IN DROSOPHILA - ANALYSIS OF THE SURVIVAL-DATA AND PRESENTATION OF A HYPOTHESIS ON THE GENETIC-REGULATION OF LONGEVITY [J].