COMPLIANCE MISMATCH AND FORMATION OF DISTAL ANASTOMOTIC INTIMAL HYPERPLASIA IN EXTERNALLY STIFFENED AND LUMEN-ADAPTED VENOUS GRAFTS

被引:69
作者
TRUBEL, W
SCHIMA, H
MORITZ, A
RADERER, F
WINDISCH, A
ULLRICH, R
WINDBERGER, W
LOSERT, U
POLTERAUER, P
机构
[1] Department of Vascular Surgery, University of Vienna, School of Medicine, Vienna
[2] Center for Biomedical Research, University of Vienna, School of Medicine, Vienna
[3] Department of Cardio-Thoracic Surgery, University of Vienna, School of Medicine, Vienna
[4] Institute of Anatomy, University of Vienna, School of Medicine, Vienna
[5] Department of Ultrastructural Pathology and Cell Biology, University of Vienna, School of Medicine, Vienna
[6] Ludwig Boltzmann Institute for Cardiosurgical Research, University of Vienna, School of Medicine, Vienna
关键词
COMPLIANCE MISMATCH; INTIMAL HYPERPLASIA; DISTAL ANASTOMOSIS; AUTOLOGOUS GRAFTS; ADAPTATION OF VENOUS GRAFT LUMEN;
D O I
10.1016/S1078-5884(05)80163-7
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objective: Compliance and formation of distal anstomotic intimal hyperplasia (DAIH) were investigated in externally stiffened venous grafts of varying calibers. Methods: 36 femoropopliteal reconstructions were performed in 18 sheep. The autologous venous grafts were inserted into tubes made of Dacron mesh to achieve compliance-mismatch and lumen adaptation Compliance tons measured by echo-tracked ultrasonography and profiles of DAIH were generated from histologic sections harvested after 8.3 months. Main results: The external mesh tube significantly lowered the local compliance of graft and host artery. DAIH appeared extensively in those groups where mesh tube constricted venous grafts met untreated host arteries (p = 0.002). No differences in compliance and DAIH formation were observed when grafts with large and adapted diameters were compared. Conclusions: For prevention of DAIH the distal venous graft diameter is not important, while the local compliance of an autologous vein is a predictive factor for DAIH formation and thus long-term patency.
引用
收藏
页码:415 / 423
页数:9
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