INCIDENCE OF LOW-FLUORESCENCE A SATELLITE REGION ON CHROMOSOME-21 ESCAPING DETECTION OF ANEUPLOIDY AT INTERPHASE BY FISH

被引：16

作者：

BOSSUYT, PJ ^{[1
]}

VANTIENEN, MN ^{[1
]}

DEGRUYTER, L ^{[1
]}

SMETS, V ^{[1
]}

DUMON, J ^{[1
]}

WAUTERS, JG ^{[1
]}

机构：

[1] UNIV INSTELLING ANTWERP,DEPT MED GENET,B-2610 WILRIJK,BELGIUM

来源：

CYTOGENETICS AND CELL GENETICS | 1995年 / 68卷 / 3-4期

关键词：

D O I：

10.1159/000133914

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Aneuploidy detection for chromosome 21 by fluorescence in situ hybridization (FISH) to interphase nuclei using a probe specific for the alphoid DNA sequences D21Z1/D13Z1 should be avoided. An extreme heteromorphism, resulting in misdiagnosis if interphase FISH is the only test employed, may be far more frequent (4/101) than expected.

引用

页码：203 / 206

页数：4

共 22 条

[1]

ADINOLFI M, 1992, ADV GENOME BIOL, V1, P301

[2] INTERPHASE CYTOGENETICS OF BRAIN-TUMORS [J].

ARNOLDUS, EPJ ;

NOORDERMEER, IA ;

PETERS, ACB ;

VOORMOLEN, JHC ;

BOTS, GTAM ;

RAAP, AK ;

VANDERPLOEG, M .

GENES CHROMOSOMES & CANCER, 1991, 3 (02) :101-107

[3]

BARTSCH O, 1991, CLIN GENET, V40, P47

[4] DA/DAPI HETEROMORPHISMS IN ACROCENTRIC CHROMOSOMES OTHER THAN 15 [J].

BUHLER, EM ;

MALIK, NJ .

CYTOGENETICS AND CELL GENETICS, 1988, 47 (1-2) :104-105

[5] 2 SUBSETS OF HUMAN ALPHOID REPETITIVE DNA SHOW DISTINCT PREFERENTIAL LOCALIZATION IN THE PERICENTRIC REGIONS OF CHROMOSOME-13, CHROMOSOME-18, AND CHROMOSOME-21 [J].

DEVILEE, P ;

CREMER, T ;

SLAGBOOM, P ;

BAKKER, E ;

SCHOLL, HP ;

HAGER, HD ;

STEVENSON, AFG ;

CORNELISSE, CJ ;

PEARSON, PL .

CYTOGENETICS AND CELL GENETICS, 1986, 41 (04) :193-201

[6]

Gray J W, 1991, Baillieres Clin Haematol, V4, P683

[7] ORGANIZATION, POLYMORPHISM, AND MOLECULAR CYTOGENETICS OF CHROMOSOME-SPECIFIC ALPHA-SATELLITE DNA FROM THE CENTROMERE OF CHROMOSOME-2 [J].

HAAF, T ;

WILLARD, HF .

GENOMICS, 1992, 13 (01) :122-128

[8]

KLINGER K, 1992, AM J HUM GENET, V51, P55

[9]

KUO WL, 1991, AM J HUM GENET, V49, P112

[10] PAINTING OF DEFINED CHROMOSOMAL REGIONS BY INSITU SUPPRESSION HYBRIDIZATION OF LIBRARIES FROM LASER-MICRODISSECTED CHROMOSOMES [J].

LENGAUER, C ;

ECKELT, A ;

WEITH, A ;

ENDLICH, N ;

PONELIES, N ;

LICHTER, P ;

GREULICH, KO ;

CREMER, T .

CYTOGENETICS AND CELL GENETICS, 1991, 56 (01) :27-30

← 1 2 3 →