INHIBITION OF 1ST-PASS METABOLISM IN CANCER-CHEMOTHERAPY - INTERACTION OF 6-MERCAPTOPURINE AND ALLOPURINOL

被引：127

作者：

ZIMM, S ^{[1
]}

COLLINS, JM ^{[1
]}

ONEILL, D ^{[1
]}

CHABNER, BA ^{[1
]}

POPLACK, DG ^{[1
]}

机构：

[1] NCI,DIV CANC TREATMENT,CLIN PHARMACOL BRANCH,BETHESDA,MD 20205

来源：

关键词：

D O I：

10.1038/clpt.1983.254

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：810 / 817

页数：8

共 23 条

[1] NONCOMPARTMENTAL DETERMINATION OF THE STEADY-STATE VOLUME OF DISTRIBUTION
BENET, LZ
GALEAZZI, RL
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (08) : 1071 - 1074
[2] CLINICAL EVALUATION OF A NEW ANTIMETABOLITE, 6-MERCAPTOPURINE, IN THE TREATMENT OF LEUKEMIA AND ALLIED DISEASES
BURCHENAL, JH
MURPHY, ML
ELLISON, RR
SYKES, MP
TAN, TC
LEONE, LA
KARNOFSKY, DA
CRAVER, LF
DARGEON, HW
RHOADS, CP
[J]. BLOOD, 1953, 8 (11) : 965 - 999
[3] COFFEY JJ, 1972, CANCER RES, V32, P1283
[4] DING TL, 1979, DRUG METAB DISPOS, V7, P373
[5] ELION GB, 1963, CANCER RES, V23, P1207
[6] POTENTIATION BY INHIBITION OF DRUG DEGRADATION - 6-SUBSTITUTED PURINES AND XANTHINE OXIDASE
ELION, GB
RUNDLES, RW
NATHAN, H
CALLAHAN, S
HITCHINGS, GH
BIEBER, S
[J]. BIOCHEMICAL PHARMACOLOGY, 1963, 12 (01) : 85 - &
[7] ELION GB, 1967, FED PROC, V26, P898
[8] DEPLETION OF ERYTHROCYTE PHOSPHORIBOSYLPYROPHOSPHATE IN MAN - A NEWLY OBSERVED EFFECT OF ALLOPURINOL
FOX, IH
WYNGAARD.JB
KELLEY, WN
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1970, 283 (22) : 1177 - &
[9] Gibaldi M, 1975, PHARMACOKINETICS, P281
[10] HAMILTON L, 1954, Ann N Y Acad Sci, V60, P304