CHARACTERIZATION OF AN APHIDICOLIN-RESISTANT MUTANT OF HERPES-SIMPLEX VIRUS TYPE-2 WHICH INDUCES AN ALTERED VIRAL-DNA POLYMERASE

被引：40

作者：

NISHIYAMA, Y

SUZUKI, S

YAMAUCHI, M

MAENO, K

YOSHIDA, S

机构：

[1] HOKKAIDO UNIV,FAC PHARMACEUT SCI,SAPPORO,HOKKAIDO 060,JAPAN

[2] INST DEV RES,DEPT BIOCHEM,KASUGAI,AICHI 48003,JAPAN

来源：

VIROLOGY | 1984年 / 135卷 / 01期

关键词：

D O I：

10.1016/0042-6822(84)90119-3

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

引用

页码：87 / 96

页数：10

共 27 条

[1] SUSCEPTIBILITY OF PHOSPHONOFORMIC ACID-RESISTANT HERPES-SIMPLEX VIRUS VARIANTS TO ARABINOSYLNUCLEOSIDES AND APHIDICOLIN [J].

BASTOW, KF ;

DERSE, DD ;

CHENG, YC .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1983, 23 (06) :914-917

[2] PHYSICAL AND GENETIC-ANALYSIS OF THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE LOCUS [J].

CHARTRAND, P ;

CRUMPACKER, CS ;

SCHAFFER, PA ;

WILKIE, NM .

VIROLOGY, 1980, 103 (02) :311-326

[3] MUTATIONS IN THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE GENE CONFERRING HYPERSENSITIVITY TO APHIDICOLIN [J].

COEN, DM ;

FURMAN, PA ;

ASCHMAN, DP ;

SCHAFFER, PA .

NUCLEIC ACIDS RESEARCH, 1983, 11 (15) :5287-5297

[4] MUTATIONS IN THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE GENE CAN CONFER RESISTANCE TO 9-BETA-D-ARABINOFURANOSYLADENINE [J].

COEN, DM ;

FURMAN, PA ;

GELEP, PT ;

SCHAFFER, PA .

JOURNAL OF VIROLOGY, 1982, 41 (03) :909-918

[5] INHIBITION OF HERPES-SIMPLEX VIRUS-INDUCED DNA-POLYMERASE, CELLULAR DNA POLYMERASE-ALPHA AND VIRUS PRODUCTION BY APHIDICOLIN [J].

DICIOCCIO, RA ;

CHADHA, K ;

SRIVASTAVA, BIS .

BIOCHIMICA ET BIOPHYSICA ACTA, 1980, 609 (02) :224-231

[6] MUTANTS OF HERPES-SIMPLEX VIRUS TYPE-1 AND TYPE-2 THAT ARE RESISTANT TO PHOSPHONOACETIC ACID INDUCE ALTERED DNA-POLYMERASE ACTIVITIES IN INFECTED-CELLS [J].

HAY, J ;

SUBAKSHARPE, JH .

JOURNAL OF GENERAL VIROLOGY, 1976, 31 (APR) :145-148

[7] HERPES-SIMPLEX VIRUS-RESISTANCE AND SENSITIVITY TO PHOSPHONOACETIC ACID [J].

HONESS, RW ;

WATSON, DH .

JOURNAL OF VIROLOGY, 1977, 21 (02) :584-600

[8] APHIDICOLIN PREVENTS MITOTIC CELL-DIVISION BY INTERFERING WITH ACTIVITY OF DNA POLYMERASE-ALPHA [J].

IKEGAMI, S ;

TAGUCHI, T ;

OHASHI, M .

NATURE, 1978, 275 (5679) :458-460

[9] PROPERTIES OF HERPES-SIMPLEX VIRUS-DNA POLYMERASE AND CHARACTERIZATION OF ITS ASSOCIATED EXONUCLEASE ACTIVITY [J].

KNOPF, KW .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1979, 98 (01) :231-244

[10] PHYSICAL MAPPING OF DRUG-RESISTANCE MUTATIONS DEFINES AN ACTIVE-CENTER OF THE HERPES-SIMPLEX VIRUS-DNA POLYMERASE ENZYME [J].

KNOPF, KW ;

KAUFMAN, ER ;

CRUMPACKER, C .

JOURNAL OF VIROLOGY, 1981, 39 (03) :746-757

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