DEOXYOLIGONUCLEOTIDES WITH INVERTED POLARITY - SYNTHESIS AND USE IN TRIPLE-HELIX FORMATION

被引：32

作者：

MCCURDY, S ^{[1
]}

MOULDS, C ^{[1
]}

FROEHLER, B ^{[1
]}

机构：

[1] GILEAD SCI INC,344-346 LAKESIDE DR,FOSTER CITY,CA 94404

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 1-3期

关键词：

D O I：

10.1080/07328319108046461

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Deoxyoligonucleotides with inverted polarity (containing a 3'-3' junction) are described. The ability of these oligonucleotides to bind to duplex DNA utilizing various linker elements is discussed.

引用

页码：287 / 290

页数：4

共 5 条

[1] SYNTHESIS OF DNA VIA DEOXYNUCLEOSIDE H-PHOSPHONATE INTERMEDIATES
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[J]. NUCLEIC ACIDS RESEARCH, 1986, 14 (13) : 5399 - 5407
[2] RECOGNITION OF MIXED-SEQUENCE DUPLEX DNA BY ALTERNATE-STRAND TRIPLE-HELIX FORMATION
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1990, 112 (06) : 2435 - 2437
[3] A CONVENIENT AND GENERAL-APPROACH TO THE SYNTHESIS OF PROPERLY PROTECTED D-NUCLEOSIDE-3'-HYDROGENPHOSPHONATES VIA PHOSPHITE INTERMEDIATES
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[J]. TETRAHEDRON LETTERS, 1986, 27 (23) : 2661 - 2664
[4] SEQUENCE-SPECIFIC CLEAVAGE OF DOUBLE HELICAL DNA BY TRIPLE HELIX FORMATION
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[J]. SCIENCE, 1987, 238 (4827) : 645 - 650
[5] PARALLEL STRANDED DNA
VANDESANDE, JH
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VONKITZING, E
PON, RT
CLEGG, RC
JOVIN, TM
[J]. SCIENCE, 1988, 241 (4865) : 551 - 557

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