A TECHNIQUE FOR STUDYING THE FUNCTION OF AN ISOLATED, PERFUSED AND VENTILATED LUNG IN A RAT MODEL

被引：11

作者：

HOPKINSON, DN

ODOM, NJ

ELOAKLEY, RM

AU, J

HOOPER, TL

机构：

[1] WYTHENSHAWE HOSP,DEPT CARDIOTHORAC SURG,MANCHESTER M23 9LT,LANCS,ENGLAND

[2] MANCHESTER ROYAL INFIRM,MANCHESTER M13 9WL,LANCS,ENGLAND

来源：

LABORATORY ANIMALS | 1995年 / 29卷 / 01期

关键词：

LUNG; PRESERVATION; MODEL;

D O I：

10.1258/002367795780740456

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

We describe a technique which allows perfusion of an isolated, ventilated rat lung with an extracorporeal veno-venous circuit from a support animal. This model provides stable and reliable function of the isolated lung for up to 3 h, thus overcoming some of the disadvantages of previous models. It may prove a potentially useful model for assessing ischaemic lung injury.

引用

页码：96 / 101

页数：6

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