STUDIES OF A NEW RICKETTSIOSIS-ASTRAKHAN SPOTTED-FEVER

被引：29

作者：

TARASEVICH, IV

MAKAROVA, VA

FETISOVA, NF

STEPANOV, AV

MISKAROVA, ED

RAOULT, D

机构：

[1] Gamaleya Institute for Epidemiology and Microbiology, U.S.S.R., Academy of Medical Sciences, Moscow

[2] Astrakhan Branch - Institute of Epidemiology, Ministry of Health of the U.S.S.R., Astrakhan

[3] Unite des rickettsies, Centre Hospitalo-Universitaire la Timone, Marseille

来源：

EUROPEAN JOURNAL OF EPIDEMIOLOGY | 1991年 / 7卷 / 03期

关键词：

SPOTTED FEVER GROUP RICKETTSIOSIS; ASTRAKHAN SPOTTED FEVER; EPIDEMIOLOGY;

D O I：

10.1007/BF00145681

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The acute febrile disease with characteristic rash seen in Astrakhan region and named as "viral exanthema of unknown etiology" was proved to be a spotted fever group rickettsiosis. Serological examination of humans from endemic areas by complement fixation test revealed antibodies to R. conorii, R. akari and strains Netsvetaev and AR-74 of R. sibirica in titres from 20 to 640 in sera from ill persons. Of 429 sera from healthy persons, 5.1% were serologically positive in a titre of 20-40. The presence of spotted fever group rickettsiae was detected in 8 of 104 Rhipicephalus sanguineus ticks removed from dogs and tested by haemocyte test with Gimenez staining and indirect immunofluorescence technique. Attempts at isolation of rickettsiae in guinea pigs and cell cultures resulted in appearance of specific spotted fever group rickettsiae antibodies in guinea pigs (4 of 8 samples examined were positive) and detection of rickettsiae by immunofluorescence technique in cell cultures (in 2 of 12 samples tested).

引用

页码：294 / 298

页数：5

共 8 条

[1]

Gross EM., Yagupsky P., Israeli rickettsial spotted fever in children, Acta Trop. Basel, 44, pp. 91-96, (1987)

[2]

Hattwick M.A.W., O'Brien R.J., Hanson B.F., Rocky Mountain spotted fever: epidemiology of an increasing problem, Ann. Intern. Med., 84, pp. 732-739, (1976)

[3]

Mahara F., Koga K., Sawada S., The first report of the rickettsial infections of Spotted Fever group in Japan. Three clinical cases, J. Jap. Assoc. Inf. Dis., 59, pp. 1165-1172, (1985)

[4]

Mansueto S., Tringali G., Walker D.H., Widespread, simultaneous increase in the incidence of Spotted Fever group rickettsioses, J. Infect. Dis., 154, pp. 539-540, (1986)

[5]

Marrero M., Raoult D., Centrifugation —shell vial technique for rapid detection of Spotted Fever group rickettsiae in blood culture, Am. J. Trop. Med. Hyg., 40, pp. 197-199, (1989)

[6]

Philip CB., Hughes L.E., Rao K.N.A., Kalra S.L., Studies on “Indian Tick Typhus” and its relation to other human, typhus - like rickettsioses, Arq. V. Congr. Int. Micr., Rio de Janeiro, 1, pp. 571-574, (1950)

[7]

Raoult D., Weiller P.J., Changnon A., Chaudet H., Gallais H., Casanova P., Mediterranean spotted fever: clinical, laboratory and epidemiological features of 199 cases, Am. J. Trop. Med. Hyg., 35, pp. 845-850, (1986)

[8]

Wang J.G., Walker D.H., Li H., Lenz H.L., Jerrells T.R., Barbash strain spotted fever group rickettsia is a strain of R. conorii and differs from R. sibirica, Acta Virol, 31, pp. 489-498, (1987)

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