ADENOSINE RECEPTORS IN ISOLATED TISSUE PREPARATIONS

被引：5

作者：

COLLIS, MG

机构：

[1] ICI Pharmaceuticals, SK10 4TG, Mereside, Alderley Park, Macclesfield

来源：

NUCLEOSIDES & NUCLEOTIDES | 1991年 / 10卷 / 05期

关键词：

D O I：

10.1080/07328319108047243

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Adenosine receptors in isolated tissues from guinea-pigs have been investigated using agonists and antagonists. The receptor mediating decreases in rate and force of contraction of the atria is of the A1 sub-type. Responses of smooth muscle preparations to adenosine and its analogues are complex involving relaxation mediated by both A2 receptors an by non-receptor mechanisms. Contractions mediated by an A1 receptor can also be detected.

引用

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页码：1057 / 1066

页数：10

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