MULTIPLE PRIMARY-CARCINOMA OF THE ESOPHAGUS

被引：17

作者：

MIZOBUCHI, S

KATO, H

TACHIMORI, Y

WATANABE, H

YAMAGUCHI, H

ITABASHI, M

机构：

[1] Department of Surgery, National Cancer Center Hospital, Tokyo

[2] Department of Endoscopy, National Cancer Center Hospital, Tokyo

[3] Pathology Division, National Cancer Center Research Institute, Tokyo

来源：

SURGICAL ONCOLOGY-OXFORD | 1993年 / 2卷 / 04期

关键词：

ALCOHOL DRINKING; CARCINOGENESIS OF MULTIPLE CARCINOMA; ESOPHAGEAL CARCINOMA; LUGOL STAIN; MULTIPLE PRIMARY ESOPHAGEAL CARCINOMA; SMOKING;

D O I：

10.1016/0960-7404(93)90014-P

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A retrospective evaluation of 239 patients with primary oesophageal carcinoma who underwent oesophagectomy without preoperative treatment revealed 45 cases (18.8%) of multiple primary oesophageal carcinoma (MPEC). The average age of the patients with MPEC was significantly lower than that of patients with single primary oesophageal carcinoma (SPEC) (P = 0.005). The incidence of association with pharyngeal malignancy was higher in patients with MPEG than in those with SPEC (P = 0.080). The number of patients in the category representing a combination of heaviest alcohol and cigarette use was significantly higher in the MPEC patients (P = 0.035). The high incidence of MPEC points to a need for careful checking of the oesophagus at the time of surgical treatment for oesophageal carcinoma. Low age at onset, a combination of heavy smoking and drinking, and association with pharyngeal malignancy are considered to be high-risk factors for MPEC.

引用

页码：249 / 253

页数：5

共 20 条

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