PHARMACOKINETICS OF NALOXONE IN RATS AND IN MAN - BASIS FOR ITS POTENCY AND SHORT DURATION OF ACTION

被引：305

作者：

NGAI, SH

BERKOWITZ, BA

YANG, JC

HEMPSTEAD, J

SPECTOR, S

机构：

[1] COLUMBIA UNIV,COLL PHYS & SURG,DEPT ANESTHESIOL,NEW YORK,NY 10032

[2] COLUMBIA UNIV,COLL PHYS & SURG,DEPT PHARMACOL,NEW YORK,NY 10032

[3] ROCHE INST MOLEC BIOL,DEPT PHYSIOL CHEM,NUTLEY,NJ 07110

来源：

ANESTHESIOLOGY | 1976年 / 44卷 / 05期

关键词：

D O I：

10.1097/00000542-197605000-00008

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

引用

页码：398 / 401

页数：4

共 9 条

[1]

BERKOWITZ BA, 1975, J PHARMACOL EXP THER, V195, P499

[2]

BERKOWITZ BA, 1975, CLIN PHARMACOL THER, V17, P629

[3] DEGREE AND DURATION OF REVERSAL BY NALOXONE OF EFFECTS OF MORPHINE IN CONSCIOUS SUBJECTS [J].

EVANS, JM ;

HOGG, MIJ ;

LUNN, JN ;

ROSEN, M .

BRITISH MEDICAL JOURNAL, 1974, 2 (5919) :589-591

[4] ANTAGONISM OF MORPHINE ANESTHESIA BY NALOXONE [J].

HASBROUC.JD .

ANESTHESIA AND ANALGESIA CURRENT RESEARCHES, 1971, 50 (06) :954-&

[5]

HEISTERKAMP DV, 1974, ANESTH ANALG, V53, P12

[6] REVERSAL OF MORPHINE ANESTHESIA WITH NALOXONE [J].

JOHNSTONE, RE ;

JOBES, DR ;

KENNELL, EM ;

BEHAR, MG ;

SMITH, TC .

ANESTHESIOLOGY, 1974, 41 (04) :361-367

[7] MICROELECTROMETRIC TITRATION MEASUREMENT OF PKAS AND PARTITION AND DRUG DISTRIBUTION COEFFICIENTS OF NARCOTICS AND NARCOTIC-ANTAGONISTS AND THEIR PH AND TEMPERATURE-DEPENDENCE [J].

KAUFMAN, JJ ;

SEMO, NM ;

KOSKI, WS .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (07) :647-655

[8]

SPECTOR S, 1971, J PHARMACOL EXP THER, V178, P253

[9]

WEINSTEIN SH, 1973, NARCOTIC ANTAGONISTS, P525

← 1 →