MYOTONIA INDUCED IN DENERVATED MUSCLES

被引：13

作者：

EBERSTEIN, A ^{[1
]}

GOODGOLD, J ^{[1
]}

JOHNSTON, R ^{[1
]}

机构：

[1] NYU, MED CTR, INST REHABIL MED, NEW YORK, NY 10016 USA

来源：

EXPERIMENTAL NEUROLOGY | 1976年 / 51卷 / 01期

关键词：

D O I：

10.1016/0014-4886(76)90070-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Diazacholesterol, an inhibitor of cholesterol biosynthesis, can alter the electrical and mechanical properties of denervated muscles in rats, resembling the changes characteristic of myotonia. Prolonged relaxation time of the muscle contraction, extended electrical activity following needle movement or percussion, and occasional myotonic responses observed in the denervated muscles after treatment, support the conclusion that the nerve supply is not an essential prerequisite for inducing myotonia.

引用

页码：266 / 270

页数：5

共 8 条

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