CONTROLLING THE DISSOCIATION OF PEPTIDE IONS USING LASER DESORPTION CHEMICAL IONIZATION FOURIER-TRANSFORM MASS-SPECTROMETRY

被引：28

作者：

SPEIR, JP ^{[1
]}

GORMAN, GS ^{[1
]}

CORNETT, DS ^{[1
]}

AMSTER, IJ ^{[1
]}

机构：

[1] UNIV GEORGIA,DEPT CHEM,ATHENS,GA 30602

来源：

ANALYTICAL CHEMISTRY | 1991年 / 63卷 / 01期

关键词：

D O I：

10.1021/ac00001a011

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Chemical ionization is demonstrated for peptide molecules evaporated by an excimer laser, operated at 193 nm. Ammonium ion chemical ionization of Val-Ala and Val-Pro-Leu confirms that peptide; molecules are evaporated by the laser as intact neutrals, without any observable fragmentation. Extensive fragmentation is observed when protonated ethylene or protonated nitrous oxide are used as reagent ions. The extent and type of fragmentations observed are correlated with the proton affinity of the reagent ion species.

引用

页码：65 / 69

页数：5

共 28 条

[1] CHEMICAL IONIZATION OF LASER-DESORBED NEUTRALS IN A FOURIER-TRANSFORM MASS-SPECTROMETER [J].