SYNTHESIS OF BIOSYNTHETIC INHIBITORS OF THE SEX-PHEROMONE OF SPODOPTERA-LITTORALIS .1. ACETYLENIC AND CYCLOPROPANE FATTY-ACIDS

被引：16

作者：

CAMPS, F

HOSPITAL, S

ROSELL, G

DELGADO, A

GUERRERO, A

机构：

[1] CSIC,CID,DEPT BIOL ORGAN CHEM,JORDI GIRONA SALGADO 18-26,E-08034 BARCELONA,SPAIN

[2] FAC PHARM,DEPT PHARMACOL & MED CHEM,E-08028 BARCELONA,SPAIN

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 1992年 / 61卷 / 02期

关键词：

INHIBITION; BETA-OXIDATION; SPODOPTERA-LITTORALIS; ACETYLENIC FATTY ACIDS; CYCLOPROPANE FATTY ACIDS;

D O I：

10.1016/0009-3084(92)90008-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The synthesis of new acetylenic and cyclopropane fatty acids, as potential inhibitors of the beta-oxidation step in the proposed biosynthesis of the sex pheromone of the Egyptian armyworm Spodoptera littoralis, is reported. The biological activity of the compounds has been determined by in vitro and in vivo bioassays, and among all the compounds tested, dichlorocyclopropane acid has shown the highest inhibition activity displayed so far.

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页码：157 / 167

页数：11

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