SYNTHESIS AND CALCIUM-CHANNEL ANTAGONIST ACTIVITY OF DIALKYL 1,4-DIHYDRO-2,6-DIMETHYL-4-(PYRIDINYL)-3,5-PYRIDINEDICARBOXYLATES

被引：57

作者：

DAGNINO, L

LIKWONGKEN, MC

WOLOWYK, MW

WYNN, H

TRIGGLE, CR

KNAUS, EE

机构：

[1] UNIV ALBERTA,FAC PHARM & PHARMACEUT SCI,EDMONTON T6G 2N8,ALBERTA,CANADA

[2] MEM UNIV NEWFOUNDLAND,FAC MED,ST JOHNS A1B 3V6,NEWFOUNDLAND,CANADA

来源：

关键词：

D O I：

10.1021/jm00162a016

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：2524 / 2529

页数：6

共 25 条

[1] EFFECTS OF 5 DIFFERENT ORGANIC CALCIUM-ANTAGONISTS ON GUINEA-PIG ISOLATED TRACHEA
ADVENIER, C
CERRINA, J
DUROUX, P
FLOCH, A
RENIER, A
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1984, 82 (03) : 727 - 733
[2] ANTMAN E, 1983, CALCIUM CHANNEL BLOC, P177
[3] BOLGER GT, 1983, J PHARMACOL EXP THER, V225, P291
[4] 4-ARYLDIHYDROPYRIDINES, A NEW CLASS OF HIGHLY-ACTIVE CALCIUM-ANTAGONISTS
BOSSERT, F
MEYER, H
WEHINGER, E
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1981, 20 (09): : 762 - 769
[5] BOSSERT F, 1979, ARZNEIMITTEL-FORSCH, V29-1, P226
[6] CRYSTAL-STRUCTURES AND PHARMACOLOGICAL ACTIVITY OF CALCIUM-CHANNEL ANTAGONISTS - 2,6-DIMETHYL-3,5-DICARBOMETHOXY-4-(UNSUBSTITUTED, 3-METHYL-PHENYL, 4-METHYL-PHENYL, 3-NITRO-PHENYL, 4-NITRO-PHENYL, AND 2,4-DINITROPHENYL)-1,4-DIHYDROPYRIDINE
FOSSHEIM, R
SVARTENG, K
MOSTAD, A
ROMMING, C
SHEFTER, E
TRIGGLE, DJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (02) : 126 - 131
[7] FRANCKOWIAK G, 1983, Patent No. 3130041
[8] GROSS CJ, 1984, J CARDIOVASC PHARM, V6, P61
[9] Hantzsch A., 1882, LIEBIGS ANN-RECL, V215, P1, DOI DOI 10.1002/JLAC.18822150102
[10] NIFEDIPINE PREVENTS SYMPATHETIC VASOCONSTRICTION DISTAL TO SEVERE CORONARY STENOSES
HEUSCH, G
DEUSSEN, A
[J]. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1984, 6 (03) : 378 - 383