THE HUMAN-IMMUNOGLOBULIN V-H REPERTOIRE

被引：370

作者：

COOK, GP

TOMLINSON, IM

机构：

来源：

IMMUNOLOGY TODAY | 1995年 / 16卷 / 05期

关键词：

D O I：

10.1016/0167-5699(95)80166-9

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A complete map of the human immunoglobulin V-H locus On chromosome 14 has recently been constructed. The locus is 1100 Kb in length and contains 51 functional V-H segments interspersed amongst a similar number of pseudogenes. Here, Graham Cook and lan Tomlinson review the organization of the locus, its polymorphism and the repertoire it encodes.

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页码：237 / 242

页数：6

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