THE LPR AND GLD GENES IN SYSTEMIC AUTOIMMUNITY - LIFE AND DEATH IN THE FAS LANE

被引：187

作者：

COHEN, PL ^{[1
]}

EISENBERG, RA ^{[1
]}

机构：

[1] UNIV N CAROLINA,SCH MED,DEPT MICROBIOL IMMUNOL,CHAPEL HILL,NC 27599

来源：

IMMUNOLOGY TODAY | 1992年 / 13卷 / 11期

关键词：

D O I：

10.1016/0167-5699(92)90066-G

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The single gene lpr and gld models of spontaneous systemic autoimmunity have attracted much attention in recent years. Here, Philip Cohen and Robert Eisenberg describe the fascinating recent findings that the lpr and Fas phenotypes result from defects in the Fas gene and, perhaps, in the ligand for fas, respectively.

引用

页码：427 / 428

页数：2

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