SCANNING ELECTRON-MICROSCOPY EVALUATION OF THE ABIOMED 5000 VENTRICULAR SUPPORT SYSTEM AFTER CLINICAL BIVENTRICULAR ASSISTANCE

被引：5

作者：

BOHLE, AS ^{[1
]}

SIEVERS, HH ^{[1
]}

BERNHARD, A ^{[1
]}

机构：

[1] UNIV KIEL,KARDIOVASK CHIRURG ABT,ARNOLD HELLER STR 7,W-2300 KIEL 1,GERMANY

来源：

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY | 1990年 / 4卷 / 12期

关键词：

THROMBUS FORMATION; MECHANICAL ASSIST DEVICE; SCANNING ELECTRON MICROSCOPY;

D O I：

10.1016/1010-7940(90)90060-D

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Twenty-nine days after implantation of an Abiomed 5000 biventricular support system for otherwise intractable end-stage cardiomyopathy, the inner surfaces of the device were examined by means of scanning electron microscopy (SEM). SEM showed clean surfaces inside the blood sacs, with only rare fibrin deposits. There were platelet adhesions on the ventricular side of the artificial atrioventricular valves; no deposits were on the opposite side. Structural deterioration of the closing edge of the artificial valves could be seen. The tubing system was likewise covered by a uniform deposition of single patelets with no major thrombus formation. Postmortem examination of the patient, on the other hand, revealed gross thrombus formation inside both atria at the cannulation sites, despite efficient anticoagulation. We conclude that the Abiomed 5000 per se is unlikely to be the site of major thrombus formation leading to subsequent embolization after 660 h implantation. However, the structural integrity of the adapting areas of the leaflets may become a point of concern. Further research is necessary to improve the atrial cannulation technique in order to prevent the atrial thrombus formation demonstrated as the source of systemic embolization.

引用

页码：671 / 674

页数：4

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