Polyphenols are medicine: Is it time to prescribe red wine for our patients?

被引:36
作者
Cordova, Alfredo C. [1 ]
Sumpio, Bauer E. [2 ]
机构
[1] Lahey Clin Med Ctr, Div Surg, Burlington, MA 01803 USA
[2] Yale Univ, Sch Med, Dept Vasc Surg, 333 Cedar St,FMB 137, New Haven, CT 06510 USA
关键词
Cardiovascular disease; French Paradox; Polyphenols; Red wine;
D O I
10.1055/s-0031-1278336
中图分类号
R6 [外科学];
学科分类号
1002 [临床医学]; 100210 [外科学];
摘要
Alcohol, specifically red wine, has been suggested to play a key role in the prevention of cardiovascular disease and other chronic pathologies, including cancer. Its regular and moderate consumption has been found in numerous epidemiological studies to correlate inversely with vascular disease and mortality, despite the presence of risk factors such as high consumption of saturated fats, elevated smoking and low physical activity. This phenomenon, known as the 'French Paradox', would be explained mainly by the high levels of polyphenols present in red wine, making it more advantageous than beer, spirits and even white wine. The habit of having one or two drinks of red wine every day with meals may translate to a longer, healthier and better quality of life.
引用
收藏
页码:111 / 117
页数:7
相关论文
共 73 条
[1]
Phenolic content of various beverages determines the extent of inhibition of human serum and low-density lipoprotein oxidation in vitro: Identification and mechanism of action of some cinnamic acid derivatives from red wine [J].
AbuAmsha, R ;
Croft, KD ;
Puddey, IB ;
Proudfoot, JM ;
Beilin, LJ .
CLINICAL SCIENCE, 1996, 91 (04) :449-458
[2]
A prospective study of alcohol, smoking, caffeine, and the risk of duodenal ulcer in men [J].
Aldoori, WH ;
Giovannucci, EL ;
Stampfer, MJ ;
Rimm, EB ;
Wing, AL ;
Willett, WC .
EPIDEMIOLOGY, 1997, 8 (04) :420-424
[3]
[Anonymous], 2005, OECD HLTH DAT 2005
[4]
Red wine raises plasma HDL and preserves long-chain polyunsaturated fatty acids in rat kidney and erythrocytes [J].
Araya, J ;
Rodrigo, R ;
Orellana, M ;
Rivera, G .
BRITISH JOURNAL OF NUTRITION, 2001, 86 (02) :189-195
[5]
Bell JRC, 2000, AM J CLIN NUTR, V71, P103
[6]
Boffetta P, 1990, Epidemiology, V1, P342, DOI 10.1097/00001648-199009000-00003
[7]
Multivariate analysis of antioxidant power and polyphenolic composition in red wines [J].
Brenna, OV ;
Pagliarini, E .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2001, 49 (10) :4841-4844
[8]
Relation of smoking and alcohol and coffee consumption to active Helicobacter pylori infection: cross sectional study [J].
Brenner, H ;
Rothenbacher, D ;
Bode, G ;
Adler, G .
BRITISH MEDICAL JOURNAL, 1997, 315 (7121) :1489-1492
[9]
Risk factors for increased bone loss in an elderly population - The Rotterdam Study [J].
Burger, H ;
de Laet, CEDH ;
van Daele, PLA ;
Weel, AEAM ;
Witteman, JCM ;
Hofman, A ;
Pols, HAP .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1998, 147 (09) :871-879
[10]
Green tea and cancer in humans: A review of the literature [J].
Bushman, JL .
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 1998, 31 (03) :151-159