KEY VARIABLES IN DOSAGE FORM DESIGN

被引：8

作者：

SCHOFIELD, T

BAVITZ, JF

LEI, CM

OPPENHEIMER, L

SHIROMANI, PK

机构：

[1] Merck Sharp and Dohme Research Laboratories, West Point, PA

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1991年 / 17卷 / 07期

关键词：

D O I：

10.3109/03639049109040832

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The study described herein was undertaken to learn more about the relationships between tablet properties and formulation/process variables. Five independent variables were varied according to a central composite star design, and a number of properties have been evaluated. A discussion of various statistical procedures/issues have been examined for exploratory studies such as this one.

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页码：959 / 974

页数：16

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