THE OUTCOME OF STEVENS-JOHNSON SYNDROME TREATED WITH CORTICOSTEROIDS

被引：41

作者：

CHERIYAN, S ^{[1
]}

PATTERSON, R ^{[1
]}

GREENBERGER, PA ^{[1
]}

GRAMMER, LC ^{[1
]}

LATALL, J ^{[1
]}

机构：

[1] NW MEM HOSP,DEPT MED,DIV ALLERGY IMMUNOL,CHICAGO,IL 60611

来源：

ALLERGY PROCEEDINGS | 1995年 / 16卷 / 04期

关键词：

D O I：

10.2500/108854195778666793

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Stevens-Johnson Syndrome (SJS) may have considerable morbidity and mortality. Traditional management has been supportive with or without corticosteroids, and we have previously reported our successful experience treating 41 SJS patients with corticosteroids. We now report the outcome of prospectively ti eating 13 additional patients with SJS with high doses of corticosteroids. Thirteen consecutive patients with SJS were treated with corticosteroids at diagnosis. Their clinical course and outcomes were analyzed Drug reactions were potential precipitants of SJS in 12 patients. The percent of skin involvement ranged from 30% to 90% with eight patients having greater than 80% involvement. Bullous lesions were seen in two patients. All patients made a complete recovery. Corticosteroid therapy may be lifesaving in these patients; and in our experience, early management of SJS with high dose corticosteroids has been very effective and associated with a full recovery.

引用

页码：151 / 155

页数：5